Dexter's Laboratory episode Copping an Aptitude
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November 30, 2001
The first segment of the third episode of Season 3 (Episode 55a) is about Dexter being sent to college. In one scene Dexter is studying while three of his fellow students are playing a game that can be assumed to be Mario Kart 64. The girl says, "Ha! Eat my dust, Toad!" The boy says, "Oh yeah? Well here comes the leader shell!" The second boy then says, "Here's Lightning for both of you!" As the scene ends, Dexter tells the three to shut up, and the sound that plays when a player completes a lap can be heard.
Cartoon Network Studios, that produced Dexter's Laboratory didn't hold any right over Nintendo's Mario, but they only included a minor reference to the series.